Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

762
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
762
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

3.5K
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
3.5K
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

837
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
837
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

479
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
479

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: ASO Author Reflections: It's Time to Take Dyspepsia Seriously.

Annals of surgical oncology·2026
Same author

ASO Visual Abstract: The Full Scope-Standardization of the Use of Endoscopy for Earlier Diagnosis of Stomach Cancer in the United States.

Annals of surgical oncology·2026
Same author

ASO Author Reflections: It's Time to Take Dyspepsia Seriously.

Annals of surgical oncology·2026
Same author

The Full Scope: Standardization of the Use of Endoscopy for Earlier Diagnosis of Stomach Cancer in the USA.

Annals of surgical oncology·2026
Same author

Advancing the Evaluation and Management of CDH1-Associated Gastric Cancer.

Journal of the National Comprehensive Cancer Network : JNCCN·2025
Same author

Correction to: Survival Outcomes Between Minimally Invasive and Open Gastrectomy in Early and Locally Advanced Gastric Adenocarcinoma in a Western Center.

Journal of gastrointestinal cancer·2025

Related Experiment Video

Updated: Mar 29, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
08:51

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

10.8K

Management of Appendix Cancer.

Kaitlyn J Kelly1

  • 1Department of Surgery, University of California San Diego, San Diego, California.

Clinics in Colon and Rectal Surgery
|December 10, 2015
PubMed
Summary

Primary appendix cancers are rare and diverse. This review clarifies their classification, epidemiology, and management based on current nomenclature and expert guidelines for better diagnosis and treatment.

Keywords:
colonic-type adenocarcinomagoblet cell adenocarcinomamucinous adenocarcinomaneuroendocrine carcinoma

More Related Videos

Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma
05:22

Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma

Published on: February 13, 2026

168

Related Experiment Videos

Last Updated: Mar 29, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
08:51

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

10.8K
Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma
05:22

Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma

Published on: February 13, 2026

168

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Pathology

Background:

  • Primary appendix cancers are rare, with diverse histology and confusing historical nomenclature.
  • Diagnosis often occurs incidentally after surgery for appendicitis or presumed ovarian cancer.

Purpose of the Study:

  • To review the epidemiology, presentation, workup, staging, and management of primary appendix cancers.
  • To standardize classification using current nomenclature, broadly categorizing tumors into colonic-type/mucinous adenocarcinoma, goblet cell adenocarcinoma, or neuroendocrine carcinoma.
  • To provide a summary of management strategies based on histologic subtype and disease extent.

Main Methods:

  • Literature review focusing on primary appendix cancers.
  • Classification of tumors based on current, recommended nomenclature.
  • Summarization of expert consensus guidelines for management.

Main Results:

  • Primary appendix cancers are histologically diverse, necessitating clear classification.
  • Signet ring cell carcinoma is a feature, not a distinct entity.
  • Management is complex, depending on tumor subtype and stage, guided by retrospective data.

Conclusions:

  • Standardized nomenclature is crucial for understanding and managing primary appendix cancers.
  • Current management relies on expert consensus and retrospective data due to the rarity of prospective trials.
  • Histologic subtype and disease extent are key determinants in treatment strategies.