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Related Experiment Video

Updated: Mar 29, 2026

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
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Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Published on: April 17, 2021

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Improving Outcomes Achieved by a New Stroke Program in Hungary.

Csilla Égi1, Júlia Horváth1, Katalin Hahn1

  • 1Markusovszky University Teaching Hospital, University of Pécs, Szombathely, Hungary.

Cerebrovascular Diseases Extra
|December 10, 2015
PubMed
Summary

Implementing a "lysis alarm" program significantly improved acute ischemic stroke care, reducing door-to-needle times and decreasing mortality. This initiative increased thrombolysis rates, though further enhancements are needed for optimal patient outcomes.

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Area of Science:

  • Neurology
  • Cardiovascular Medicine
  • Public Health

Background:

  • Stroke incidence and prevalence are rising due to an aging population, leading to significant disability.
  • Despite advancements, a notable proportion of stroke patients experience severe neurological and cognitive deficits.
  • Optimized stroke center organization has demonstrably improved patient outcomes globally.

Purpose of the Study:

  • To evaluate the impact of a "lysis alarm" program on acute ischemic stroke treatment.
  • To assess changes in thrombolysis rates and door-to-needle times post-program implementation.
  • To analyze the effect of the program on stroke-related mortality.

Main Methods:

  • Retrospective review of electronic health records for acute ischemic stroke patients.
Keywords:
Public educationStrokeStroke centerStroke teamThrombolysis

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Last Updated: Mar 29, 2026

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in G&#246;ttingen Minipigs and Landrace Pigs
14:35

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Published on: April 17, 2021

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  • Comparison of data from periods before (Oct 2012-Jun 2013) and after (Oct 2013-Jun 2014) the "lysis alarm" program.
  • Analysis of thrombolysis procedure numbers, door-to-needle times, and mortality rates.

    • Main Results:

    • Thrombolysis procedures increased from 19 to 32 cases after program initiation.
    • The "door-to-needle" time decreased from 88 to 71 minutes.
    • Thrombolytic treatment mortality decreased from 16% to 9%; the center's thrombolysis rate rose to 4%.

    Conclusions:

    • The "lysis alarm" program enhanced stroke intervention and reduced mortality.
    • The achieved thrombolysis rate exceeds the national average but remains lower than Western European benchmarks.
    • Continuous refinement of the stroke program is essential to further improve patient outcomes.