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Plasmocytoma presented as pancreatic head mass
Muhammed Hatem1, Benny So1, Robin Gray1
1Foothills Medical Center, 1403 - 29 Street N.W., Calgary, AB, Canada.
Radiology Case Reports
|December 10, 2015
Summary
Multiple myeloma, a plasma cell cancer, can rarely occur outside the bone marrow. This study reports an extremely rare case of primary pancreatic plasmacytoma, highlighting its unusual presentation.
Area of Science:
- Oncology
- Hematology
- Pathology
Background:
- Multiple myeloma involves malignant plasma cell proliferation, leading to ineffective antibody production and immunosuppression.
- Extramedullary plasmacytomas, rare occurrences outside bone marrow, typically affect the chest (5%) or gastrointestinal tract (10%).
Observation:
- This report details an exceptionally rare case of primary plasmacytoma originating in the pancreas.
- Such pancreatic involvement is exceedingly uncommon in medical literature.
Findings:
- The presented case represents one of only 25 documented instances of primary pancreatic plasmacytoma in English literature.
- This highlights the potential for plasma cell neoplasms to manifest in rare anatomical locations.
Implications:
- This case expands the known spectrum of extramedullary plasmacytoma presentations.
- Increased awareness may aid in the diagnosis of rare pancreatic tumors.
- Further research into the pathogenesis and treatment of pancreatic plasmacytomas is warranted.

