Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

621
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
621
Positron Emission Tomography01:29

Positron Emission Tomography

8.0K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
8.0K
Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists01:23

Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists

602
Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
602
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

747
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
747

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluating cervical screening coverage in Royal Navy personnel at sea (2016-2023): a case study on the limitations of digital surveillance.

BMJ military health·2025
Same author

'Where are all the men?'

BMJ military health·2024
Same author

Portal hypertension in primary biliary cholangitis: prevalence, natural history and histological correlates.

European journal of gastroenterology & hepatology·2020
Same author

Lymph node harvest in colon and rectal cancer: Current considerations.

World journal of gastrointestinal surgery·2012
Same author

The malignant adenoma: when to operate and when to watch.

Surgical endoscopy·2008
Same author

Pseudohepatic tumour associated with secondary syphilis in an HIV-positive male.

International journal of STD & AIDS·2006

Related Experiment Video

Updated: Mar 29, 2026

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.8K

Pelvic radiation therapy: Between delight and disaster.

Kirsten Al Morris1, Najib Y Haboubi1

  • 1Kirsten AL Morris, University of Manchester Medical School, Manchester M13 9PT, United Kingdom.

World Journal of Gastrointestinal Surgery
|December 10, 2015
PubMed
Summary

Radiotherapy complications, known as pelvic radiation disease (PRD), affect cancer survivors. Improved awareness and management strategies are needed to address these debilitating symptoms and enhance quality of life.

Keywords:
Pelvic radiotherapyRadiationToxicity

More Related Videos

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

21.3K
Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System
08:25

Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System

Published on: April 11, 2018

16.1K

Related Experiment Videos

Last Updated: Mar 29, 2026

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.8K
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

21.3K
Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System
08:25

Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System

Published on: April 11, 2018

16.1K

Area of Science:

  • Oncology
  • Radiation Oncology
  • Gastroenterology

Background:

  • Radiotherapy is a cornerstone cancer treatment, leading to increased long-term survival.
  • Survivors often experience long-term complications, including pelvic radiation disease (PRD).
  • PRD significantly impacts patient quality of life due to its challenging symptoms.

Purpose of the Study:

  • To raise awareness of pelvic radiation disease (PRD).
  • To highlight the underappreciated burden of PRD symptoms.
  • To advocate for improved management and research in PRD.

Main Methods:

  • Review of existing literature on radiotherapy complications.
  • Analysis of the impact of PRD on patient quality of life.
  • Identification of gaps in current service provision and research.

Main Results:

  • Pelvic radiation disease (PRD) arises from radiation damage to non-cancerous tissues.
  • PRD symptoms include diarrhea, tenesmus, incontinence, and rectal bleeding.
  • Current management of PRD is often suboptimal, with significant quality of life implications.

Conclusions:

  • There is a need for greater recognition of pelvic radiation disease (PRD).
  • Enhanced service provision and dedicated research are crucial for improving patient outcomes.
  • Optimizing PRD management can significantly improve the quality of life for cancer survivors.