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Primary Left Cardiac Angiosarcoma with Mitral Valve Involvement Accompanying Coronary Artery Disease

Cagdas Baran1, Serkan Durdu1, Sadik Eryilmaz1

  • 1Department of Cardiovascular Surgery, Ankara University School of Medicine, Cebeci Heart Center, Dikimevi, 06340 Ankara, Turkey.

Case Reports in Surgery
|December 10, 2015
PubMed

Insights

A rare cardiac angiosarcoma caused myocardial infarction and severe valve issues in a 43-year-old woman. The tumor invaded heart structures, preventing extensive treatment beyond a bypass and biopsy.

Area of Science:

  • Cardiology
  • Oncology
  • Pathology

Background:

  • Primary cardiac angiosarcomas are rare tumors.
  • Cardiac tumors can present with diverse and severe cardiovascular complications.

Purpose of the Study:

  • To report a unique case of cardiac angiosarcoma presenting with non-ST elevation myocardial infarction and severe valvular dysfunction.
  • To highlight the diagnostic and therapeutic challenges posed by primary cardiac tumors.

Main Methods:

  • Case report of a 43-year-old female patient.
  • Diagnostic workup included coronary angiography.
  • Surgical exploration and biopsy were performed.

Main Results:

  • The patient presented with non-ST elevation myocardial infarction, severe mitral regurgitation, and mild mitral stenosis.
  • A primary cardiac angiosarcoma was identified, originating from the left atrial free wall and invading mitral valve structures, pulmonary veins, and pericardium.
  • Coronary angiography showed significant stenosis in the left main and left circumflex arteries.

Conclusions:

  • This case represents a unique presentation of cardiac angiosarcoma.
  • The extensive tumor invasion precluded curative surgical intervention, necessitating palliative bypass surgery and biopsy.
  • Emphasizes the importance of considering rare cardiac tumors in patients with unexplained cardiovascular symptoms.

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