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DNA Microarrays

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...

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Updated: Mar 29, 2026

Snap Chip for Cross-reactivity-free and Spotter-free Multiplexed Sandwich Immunoassays

Snap Chip for Cross-reactivity-free and Spotter-free Multiplexed Sandwich Immunoassays

Published on: November 13, 2017

Suspended Planar-Array Chips for Molecular Multiplexing at the Microscale.

Núria Torras¹, Juan Pablo Agusil², Patricia Vázquez³

¹Instituto de Microelectrónica de Barcelona, IMB-CNM (CSIC), C/dels Til·lers, Campus UAB, Cerdanyola del Vallès, Barcelona, 08193, Spain.

Advanced Materials (Deerfield Beach, Fla.)

|December 10, 2015

Summary

This summary is machine-generated.

A new suspended chip technology enables molecular multiplexing for analyzing tiny sample volumes. This innovation allows for unprecedented miniaturization, facilitating intracellular analysis of living cells.

Keywords:

chip-in-a-cell planar-arrays silicon chips single-cell analysis suspended-arrays

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Polymer Microarrays for High Throughput Discovery of Biomaterials

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Published on: January 25, 2012

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Polymer Microarrays for High Throughput Discovery of Biomaterials

Polymer Microarrays for High Throughput Discovery of Biomaterials

Published on: January 25, 2012

Area of Science:

Biotechnology
Nanotechnology
Materials Science

Background:

Current molecular analysis methods often require larger sample volumes.
Limitations exist in achieving high-throughput analysis with miniaturized platforms.

Purpose of the Study:

To introduce a novel suspended planar-array chips technology.
To demonstrate its capability for molecular multiplexing and analyzing minute sample volumes.
To enable intracellular analysis of living cells.

Main Methods:

Fabrication of suspended chips using silicon-based technology.
Application of polymer-pen lithography for pattern flexibility.
Development of a miniaturized platform for molecular analysis.

Main Results:

Achieved effective molecular multiplexing on a single suspended chip.
Demonstrated analysis of extraordinarily small sample volumes.
Enabled dramatic chip miniaturization for intracellular applications.
Obtained increased molecular pattern flexibility and parallel production capabilities.

Conclusions:

The novel suspended planar-array chips technology offers a powerful tool for high-sensitivity molecular analysis.
This technology facilitates unprecedented miniaturization, opening new avenues for intracellular studies.
The approach enhances molecular pattern flexibility and supports parallel production for broader applications.