Late results after pericardectomy for constrictive pericarditis via left thoracotomy

Pericardectomy was performed on 28 men and 8 women (mean age 56, range 18-74 years) with diagnosis constrictive pericarditis. The etiology was unknown in 16 cases. Left anterior thoracotomy was employed in all but one case, in which median sternotomy was preferred because of extensive left pleural calcifications. There were three early and 11 late deaths. Actuarial survival at 5 and 10 years was 77% and 64%, respectively. Relief of symptoms was reported by 16 of the 33 patients (49%), who survived the postoperative period. These 16 were among the 22 survivors observed for a median of 8 (range 2-17) years postoperatively. Complete pericardectomy was achieved in all 16 asymptomatic patients, but in only nine of the 17 hospital survivors (53%), with persistent heart failure (p less than 0.01). Pericardial calcifications were significantly less common in the former than in the latter group. Lack of postoperative improvement was related to severe, nonresectable calcifications, and probably in some cases to associated fibrous epicarditis or restrictive myocardial disease. Left thoracotomy permits easier and more complete left ventricular pericardectomy, but is less safe when severe calcifications involve the right ventricle and atrium.