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Related Experiment Video

Updated: Mar 29, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
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Long-term Outcomes After Radiosurgery for Temporal Bone Paragangliomas.

Stacey M Scheick1, Christopher G Morris1, Robert J Amdur1

  • 1Departments of Radiation Oncology.

American Journal of Clinical Oncology
|December 10, 2015
PubMed
Summary
This summary is machine-generated.

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Stereotactic radiosurgery (SRS) offers an 81% local control rate for temporal bone paragangliomas, demonstrating a safe and effective treatment with minimal complications. This approach is suitable for skull base tumors when fractionated radiotherapy is not feasible.

Area of Science:

  • Neurosurgery
  • Radiation Oncology
  • Otolaryngology

Background:

  • Temporal bone paragangliomas are rare tumors.
  • Stereotactic radiosurgery (SRS) is an emerging treatment option.

Purpose of the Study:

  • To evaluate the long-term outcomes of SRS for temporal bone paragangliomas.
  • To assess the safety and efficacy of SRS in managing these tumors.

Main Methods:

  • Retrospective review of 11 patients with temporal bone paragangliomas treated with SRS.
  • Median SRS dose of 15 Gy in 1 fraction.
  • Follow-up via imaging to assess local control.

Main Results:

  • 81% local control rate at 5 and 10 years.

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  • 88% cause-specific survival at 5 and 10 years.
  • 100% distant metastasis-free survival at 5 and 10 years.
  • No severe complications reported.

    • Conclusions:

    • SRS is a safe and effective treatment for benign head and neck paragangliomas.
    • SRS is a suitable alternative for skull base tumors <3 cm when fractionated radiotherapy is logistically unsuitable.
    • Alternative management options include surgery and observation based on patient health and life expectancy.