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Long-term Outcomes After Radiosurgery for Temporal Bone Paragangliomas.
Stacey M Scheick1, Christopher G Morris1, Robert J Amdur1
1Departments of Radiation Oncology.
American Journal of Clinical Oncology
|December 10, 2015
Summary
Stereotactic radiosurgery (SRS) offers an 81% local control rate for temporal bone paragangliomas, demonstrating a safe and effective treatment with minimal complications. This approach is suitable for skull base tumors when fractionated radiotherapy is not feasible.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Otolaryngology
Background:
- Temporal bone paragangliomas are rare tumors.
- Stereotactic radiosurgery (SRS) is an emerging treatment option.
Purpose of the Study:
- To evaluate the long-term outcomes of SRS for temporal bone paragangliomas.
- To assess the safety and efficacy of SRS in managing these tumors.
Main Methods:
- Retrospective review of 11 patients with temporal bone paragangliomas treated with SRS.
- Median SRS dose of 15 Gy in 1 fraction.
- Follow-up via imaging to assess local control.
Main Results:
- 81% local control rate at 5 and 10 years.
- 88% cause-specific survival at 5 and 10 years.
- 100% distant metastasis-free survival at 5 and 10 years.
- No severe complications reported.
Conclusions:
- SRS is a safe and effective treatment for benign head and neck paragangliomas.
- SRS is a suitable alternative for skull base tumors <3 cm when fractionated radiotherapy is logistically unsuitable.
- Alternative management options include surgery and observation based on patient health and life expectancy.
