Related Experiment Video
Updated: Mar 29, 2026
Multifocal Electroretinograms
Published on: December 4, 2011
Sensitivity of multifocal electroretinography (mfERG) in detecting siderosis
Shikha Gupta1, Neha Midha2, Varun Gogia2
1Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi;.
Objective:
To evaluate use of multifocal electroretinography (mfERG) in diagnosing retinal toxicity from siderosis with normal ERG.
Design:
Prospective case series.
Participants:
Six patients with retained intraocular foreign body were recruited.
Methods:
The affected eye of the patients had no clinical evidence of siderosis, had similar full-field photopic 3.0 ERG compared with the fellow eye, and had subnormal visual acuity. Group averages in each MfERG ring for implicit time and amplitude at P1 wave were compared between affected and fellow eye to look for latent siderosis.
Results:
On mfERG, no statistical difference in group averaged amplitude was observed; however, a significant difference (p < 0.05) was found in group averaged latency between fellow and affected eye at most tested rings (<2 degree, 2-5 degree, and >15 degree rings). Average latency for overall retinal area mapped also showed significant difference (p = 0.010).
Conclusions:
Increased mfERG latency may serve as an early predictor of retinal damage from siderosis when full-field ERG is normal.
