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Related Concept Videos

Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

1.8K
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
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Amyloid Fibrils03:03

Amyloid Fibrils

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Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
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Amyloid Fibrils03:03

Amyloid Fibrils

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6.9K
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

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Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
752
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

1.7K
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
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Related Experiment Video

Updated: Mar 29, 2026

Performing and Processing FNA of Anterior Fat Pad for Amyloid
09:41

Performing and Processing FNA of Anterior Fat Pad for Amyloid

Published on: October 30, 2010

56.5K

[Amyloidosis presenting as melaena].

Ester M B Jessen1, Liv Bjerre Juul Nielsen, Marie Kamper Bønnelycke

  • 1ester_jessen@hotmail.com.

Ugeskrift for Laeger
|December 15, 2015
PubMed
Summary

Gastric amyloidosis, a rare condition, can present with unspecific symptoms like melaena. Diagnosis requires biopsy, even when malignancy is suspected, as this case demonstrates.

Area of Science:

  • Gastroenterology
  • Pathology

Background:

  • Amyloidosis involves abnormal extracellular protein deposits, potentially affecting the stomach.
  • Gastric amyloidosis symptoms are rare, diffuse, and unspecific, complicating diagnosis.

Observation:

  • A 79-year-old female presented with melaena, with no prior history of amyloidosis.
  • Gastroscopy suggested a gastric malignancy, but biopsy confirmed amyloidosis.

Findings:

  • Biopsy is essential for diagnosing gastric amyloidosis, especially when symptoms are atypical.
  • This case highlights a rare presentation of gastric amyloidosis mimicking malignancy.

Implications:

  • Early diagnosis of gastric amyloidosis is crucial for appropriate management.

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Related Experiment Videos

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  • Further research into the pathogenesis and treatment of gastric amyloidosis is warranted.