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Updated: Mar 29, 2026

Orthotopic Left Lung Transplantation in Rats
Published on: July 3, 2025
Prolonged Use of the Hemolung Respiratory Assist System as a Bridge to Redo Lung Transplantation
Christian A Bermudez1, Diana Zaldonis1, Ming-Hui Fan2
1Division of Cardiothoracic Transplantation, Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania.
Abstract:
Although extracorporeal membrane oxygenation (ECMO) has been used frequently as a bridge to primary lung transplantation, active centers are conservative with this approach in patients requiring redo lung transplantation. We report the use of extracorporeal carbon dioxide removal, using the Hemolung respiratory assist system, as a prolonged bridge to lung transplantation, and the first use of the Hemolung as a bridge to redo lung transplantation. Hemolung support improved the patient's clinical status and allowed redo lung transplantation.

