[Determination of total Bromine in urine by inductively coupled plasma mass spectrometry (ICP-MS)]
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Updated: Mar 29, 2026

Speciation and Bioavailability Measurements of Environmental Plutonium Using Diffusion in Thin Films
Published on: November 9, 2015
Changmei Zhou1, Hangju Zhu, Deye Liu
1Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
Objective:
To establish a method to determine total bromine in urine.
Method:
Diluted urine samples were directly introduced into ICP-MS then quantized by standard curve.
Result:
Total bromine in urine was linear within 1.0~50 mg/L with r > 0.999, When spiked at a concentration of 0.020 mg/L, 0.050 mg/L, 0.150 mg/L, the recovery was 95%~98%, intra-assay precision was 1.4% 3.2%, inter-assay precision was 3.4% to 5.0%. Urine could store in -20 °C refrigerator 3 months without any bromine loss.
Conclusion:
Using ICP-MS to determine the urinary total bromine, the method is fast, accurate, wide linear range of features, could meet with the requirement of Part 5 of occupational health standards guide: Method determination of chemical substances in biological materials (GBZ/T 210.5-2008), a strong competitive advantage in a wide range of survey, suitable for promotion.
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