Perimenopause: From Research to Practice.
1Department of Obstetrics and Gynecology, University of Colorado School of Medicine , Aurora, Colorado.
Menopause transition brings common symptoms like hot flashes, sleep issues, mood changes, and vaginal dryness. Many women seek help, with treatments including hormone therapy and behavioral strategies.
Area of Science:
- Reproductive endocrinology and women's health.
- Understanding the biological and psychological changes during menopause.
Background:
- The menopausal transition (perimenopause) involves significant hormonal shifts and associated symptoms.
- Longitudinal studies have clarified the natural history and prevalence of menopausal symptoms.
- Nearly 90% of women seek healthcare for bothersome menopausal symptoms.
Purpose of the Study:
- To review the common symptoms experienced during the menopausal transition.
- To discuss the prevalence, duration, and interactions of these symptoms.
- To outline current clinical approaches for managing menopausal symptoms.
Main Methods:
- Review of findings from long-term, longitudinal cohort studies on women's health.
- Analysis of symptom patterns, natural history, and prevalence during perimenopause.
- Synthesis of information on clinical management strategies.
Main Results:
- Hot flashes are a classic, prevalent symptom, problematic for about one-third of women.
- Sleep disturbances, depressed mood, and anxiety increase during the menopausal transition.
- Vaginal dryness and dyspareunia affect approximately one-third of women and often require treatment.
Conclusions:
- Menopausal symptoms are highly prevalent and can significantly impact quality of life.
- Symptoms often interact, exacerbating each other.
- Management options include hormone therapy and nonhormonal/behavioral strategies.
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