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Multiplexed Activity of perAuxidase: DNA-Capped AuNPs Act as Adjustable Peroxidase
Mustafa Salih Hizir1, Meryem Top1, Mustafa Balcioglu1
1Department of Chemistry, University at Albany, State University of New York , 1400 Washington Avenue, Albany, New York 12222, United States.
Analytical Chemistry
|December 15, 2015
Abstract:
In this study, we have investigated the intrinsic peroxidase-like activity of citrate-capped AuNPs (perAuxidase) and demonstrated that the nanozyme function can be multiplexed and tuned by integrating oligonucleotides on a nanoparticle surface. Systematic studies revealed that by controlling the reaction parameters, the mutiplexing effect can be delayed or advanced and further used for aptasensor applications.
