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Pregnancy Data in a Turkish Multiple Sclerosis Population.

Ayse Altintas1, Bjar Najar, Gokcen Gozubatik-Celik

  • 1Department of Neurology, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey.

European Neurology
|December 15, 2015
PubMed
Summary
This summary is machine-generated.

Pregnancy in Turkish multiple sclerosis (MS) patients was studied. Results indicate MS does not negatively impact disease course or disability, and higher pregnancy numbers may benefit relapsing-remitting MS progression.

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Area of Science:

  • Neurology
  • Reproductive Medicine

Background:

  • Investigating pregnancy outcomes in Turkish multiple sclerosis (MS) patients.
  • First retrospective clinical study of its kind in this population.

Purpose of the Study:

  • To analyze pregnancy data in Turkish MS patients.
  • To compare fertility rates and disease progression with the general population.

Main Methods:

  • Retrospective clinical study design.
  • Evaluation of 558 pregnancies in 199 MS patients.
  • Comparison with general Turkish population fertility data.

Main Results:

  • Fertility rate in MS patients was lower than in the general population, even prior to diagnosis.
  • Higher numbers of pregnancies may favorably influence the transition from relapsing-remitting MS to secondary progressive MS.
  • No significant effect of pregnancy on reaching Expanded Disability Status Scale (EDSS) 6.0 was observed.

Conclusions:

  • Multiple sclerosis (MS) does not adversely affect the disease course or patient disability.
  • Pregnancy appears to be safe in MS patients and may offer some benefits regarding disease progression.