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An improved MR sequence for attenuation correction in PET/MR hybrid imaging.
Koji Sagiyama1, Yuji Watanabe2, Ryotaro Kamei1
1Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Magnetic Resonance Imaging
|December 15, 2015
Summary
The optimal MR sequence for PET/MR attenuation correction uses specific echo times and radial k-space sampling. This improves segmentation accuracy and reproducibility in PET/MR hybrid imaging.
Area of Science:
- Medical Imaging
- Radiology
- Biophysics
Background:
- Accurate attenuation correction is crucial for quantitative PET/MR hybrid imaging.
- Current MR-based methods require optimization for improved segmentation accuracy.
Purpose of the Study:
- To investigate the impact of MR sequence parameters on tissue segmentation for attenuation correction.
- To identify the optimal MR sequence for reliable attenuation correction in PET/MR.
Main Methods:
- Six 3D turbo-field-echo MR sequences were tested in 8 healthy volunteers.
- Parameters varied included echo time, k-space trajectory (Cartesian vs. radial), and image contrast.
- Radiologists scored segmentation accuracy and ghost artifacts; multiple regression analysis was used.
Main Results:
- 3D turbo-field-echo sequences with in-phase echo time and radial k-space sampling yielded the highest scores for segmentation accuracy and reproducibility.
- Shorter echo times and anterior/posterior Cartesian sampling resulted in lower scores.
- Radial k-space sampling significantly improved segmentation scores and reduced intrasubject variations compared to Cartesian sampling.
Conclusions:
- 3D turbo-field-echo MR sequences employing an in-phase echo time and radial k-space sampling are optimal for MR-based attenuation correction.
- These optimized sequences enhance segmentation accuracy and reproducibility in PET/MR imaging.
