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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
Published on: August 15, 2019
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The MG-RAST metagenomics database and portal in 2015
Andreas Wilke1, Jared Bischof1, Wolfgang Gerlach1
1Argonne National Laboratory, Mathematics and Computer Science Division, 60439 Argonne, IL, USA University of Chicago, Chicago 60637, IL, USA.
Nucleic Acids Research
|December 15, 2015
Summary
MG-RAST, a metagenomic data portal, now processes vast datasets with an updated workflow and scalable technology. It facilitates data sharing and integration with other analysis tools for broader research applications.
Area of Science:
- Metagenomics
- Bioinformatics
- Data Science
Background:
- MG-RAST is a widely used open-submission data portal for metagenomic datasets.
- The platform has experienced significant growth, hosting over 200,000 datasets and processing 4 terabasepairs monthly.
- Continuous updates and feature additions are essential to manage the increasing data volume.
Purpose of the Study:
- To report on the enhancements and updates made to the MG-RAST analysis workflow.
- To detail the technological advancements enabling the system to scale for high-throughput metagenomic data.
- To demonstrate the utility of MG-RAST data through integration examples with third-party tools.
Main Methods:
- Updating the analysis workflow to accommodate increased data processing demands.
- Implementing scalable technologies to manage a 4-fold increase in data submissions over 24 months.
- Developing and showcasing examples of integrating MG-RAST data with external bioinformatics tools.
Main Results:
- MG-RAST now processes an average of 4 terabasepairs of metagenomic data per month.
- The system has successfully scaled its pipeline to handle a 4-fold increase in submissions.
- Several new features have been implemented, enhancing the portal's functionality.
- Demonstrated successful integration of MG-RAST data with popular third-party analysis and sequence alignment tools.
Conclusions:
- MG-RAST provides a robust and scalable platform for metagenomic data processing and analysis.
- The portal's continuous development ensures its capacity to handle growing data volumes.
- Integration capabilities enhance the value and accessibility of metagenomic data for the scientific community.
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