Related Experiment Video
Updated: Mar 28, 2026

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
Nonoccupational Postexposure Human Immunodeficiency Virus Prophylaxis: Acceptance Following Sexual Assault
Jessica E Draughon Moret1, William E Hauda, Bonnie Price
1Jessica E. Draughon Moret, PhD, RN, SANE-A, is Assistant Professor of Clinical Nursing, Betty Irene Moore School of Nursing, University of California Davis. William E. Hauda II, MD, is Medical Director, Forensic Assessment and Consultation Team, Inova Fairfax Hospital, Falls Church, Virginia. Bonnie Price, RN, SANE-A, SANE-P, AFN-BC, is Director, Forensic Nurse Examiner Program, Bon Secours St. Mary's Hospital, Richmond, Virginia. Daniel J. Sheridan, PhD, RN, FAAN, is Professor, Goldfarb School of Nursing, Barnes-Jewish College, St. Louis, Missouri.
Background:
Nonoccupational postexposure prophylaxis (nPEP) for HIV following sexual assault may decrease the likelihood of HIV transmission.
Objective:
The purpose of this exploratory chart review study was to examine factors associated with patients accepting post-sexual assault nPEP at three forensic nurse examiner programs in urban settings.
Methods:
Forensic nursing charts of patients presenting for acute sexual assault care were reviewed as part of a mixed-methods study.
Results:
Patients assaulted by more than one or an unknown number of assailants were over 12 times more likely to accept the offer of nPEP (adjusted odds ratio [aOR] = 12.66, 95% CI [2.77, 57.82]). In cases where no condom was used (aOR = 8.57, 95% CI [1.59, 46.10]) or when any injury to the anus or genitalia was noted (aOR = 4.10, 95% CI [1.57, 10.75]), patients were more likely to accept nPEP. Patients with any injury to the face or head were less likely to initiate nPEP (aOR = 0.32, 95% CI [0.11, 0.97]).
Discussion:
This study is an important first step in understanding factors associated with nPEP acceptance after sexual assault.
Related Concept Videos
Sexually Transmitted Infections
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Retrovirus Life Cycles
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Transmission-based Precautions I: Contact, Enteric, and Droplets
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Immunodeficiency Diseases
There are three main causes of immunodeficiency...

