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Updated: Aug 7, 2026

Introduction to Solid Supported Membrane Based Electrophysiology
Published on: May 11, 2013
Electrical phenomena at the surface of phospholipid membranes relevant to the sorption of ionic compounds
1Electrotechnical Laboratory, AIST, Tsukuba-City, Ibaraki, Japan.
Abstract:
The change in electrostatical potential-profile across the phospholipid membranes caused by the binding or sorption of ionic compounds (metal cations, ionic surfactants, lipid-soluble ions, and ionophore-metal complexes) can be estimated by the direct measuring method (combination of zeta potential of lipid vesicles and surface potential of lipid monolayer). The analysis of the data by a simple electrical double layer theory reveals the binding/sorption location of these ions. The coexistent effect of metal ions and lipid-soluble ions on the sorption behavior is described from the interfacial electrochemical view point. The coagulation of lipid vesicles caused by those ionic compounds is also discussed.
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