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Laboratory Evaluation of a Dual-Path Platform Assay for Rapid Point-of-Care HIV and Syphilis Testing
S R Leon1, L B Ramos2, S K Vargas2
1Laboratory of Sexual Health, Universidad Peruana Cayetano Heredia, Lima, Peru Dirección de Investigación, Socios en Salud Sucursal del Perú, Lima, Peru srleons@gmail.com.
Abstract:
We assessed the laboratory performance of the Chembio dual-path platform HIV-syphilis rapid immunodiagnostic test and electronic reader for detection of HIV and Treponema pallidum antibodies in 450 previously characterized serum specimens. For visual or electronic reader HIV antibody detection, the sensitivity was 100% and the specificity was 98.7%. For visual T. pallidum antibody detection, the test sensitivity was 94.7% and the specificity was 100.0%; with the electronic reader, the sensitivity was 94.7% and the specificity was 99.7%.
