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Updated: Mar 28, 2026

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Three-dimensional Quantification of Intestinal Mucus Using Whole-mount Tissue Imaging
Published on: September 12, 2025
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Biological modeling of mucus to modulate mucus barriers
Jean-Luc Desseyn1, Valérie Gouyer2, Frédéric Gottrand2
1LIRIC-UMR 995, Inserm, University of Lille, Lille, France jean-luc.desseyn@inserm.fr.
American Journal of Physiology. Gastrointestinal and Liver Physiology
|December 15, 2015
Abstract:
A recent study using a transgenic mouse, whose intestinal mucus contains a molecule made of 12 copies of a domain found in many gelling mucins, demonstrates that it is possible to strengthen mucus properties in situ, leading to promising new treatment strategies in diseases in which the mucosal barrier is impaired.

