The pharmacokinetic basis of insulin therapy in diabetes mellitus

Similar glycaemic control and risk of hypoglycaemia with patient- versus physician-managed titration of insulin glargine 300 U/mL across subgroups of patients with T2DM: a post hoc analysis of ITAS.

Acta diabetologica·2021

Italian Titration Approach Study (ITAS) with insulin glargine 300 U/mL in insulin-naïve type 2 diabetes: Design and population.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2019

Clinical relevance of pharmacokinetic and pharmacodynamic profiles of insulin degludec (100, 200 U/mL) and insulin glargine (100, 300 U/mL) - a review of evidence and clinical interpretation.

Diabetes & metabolism·2018

Glycaemic control and hypoglycaemia risk with insulin glargine 300 U/mL versus glargine 100 U/mL: A patient-level meta-analysis examining older and younger adults with type 2 diabetes.

Diabetes & metabolism·2018

Assessment of hypoglycaemia during basal insulin therapy: Temporal distribution and risk of events using a predefined or an expanded definition of nocturnal events.

Diabetes & metabolism·2017

Morning administration of 0.4U/kg/day insulin glargine 300U/mL provides less fluctuating 24-hour pharmacodynamics and more even pharmacokinetic profiles compared with insulin degludec 100U/mL in type 1 diabetes.

Diabetes & metabolism·2017

Prediabetes phenotypes and the development and regression of metabolic dysfunction-associated fatty liver disease: A prospective cohort study.

Diabetes research and clinical practice·2026

Global insulin supply insecurity and the role of manufacturing innovation.

Diabetes research and clinical practice·2026

Association of peripheral neuropathy severity and cardiac autonomic dysfunction in individuals with neuropathic diabetic foot versus those with diabetic peripheral neuropathy alone.

Diabetes research and clinical practice·2026

Knowledge, health beliefs, and diabetic retinopathy screening practices among adults living with diabetes in Ebonyi state, Nigeria: a community-based cross-sectional study.

Diabetes research and clinical practice·2026

Impact of vaccination on the development of type 1 diabetes in children and vaccine safety in pediatric patients with T1DM: A systematic review.

Diabetes research and clinical practice·2026

Diabetes, Long-term mortality, and LDL-C target attainment after an acute coronary syndrome: A population-based cohort study (2016-2024).

Diabetes research and clinical practice·2026

Efficacy analysis and adverse event management of selinexor in the treatment of relapsed/refractory multiple myeloma.

Frontiers in medicine·2026

Case Report: Panic attacks after tirzepatide injection in two female patients with recurrent depressive disorder.

Frontiers in drug safety and regulation·2026

Individualized dosing in the precision medicine era: a narrative review.

Frontiers in pharmacology·2026

Targeting the Parkinson's disease interactome: a systems pharmacology and molecular dynamics investigation unveils Berberis aristata-derived phytoconstituents as potential modulators of tyrosine hydroxylase and p53: a systems and molecular dynamics investigation.

In silico pharmacology·2026

Transcriptomic insights into loperamide-induced gastric dysmotility: RNA-seq analysis of a mouse model.

Frontiers in physiology·2026

Beyond pharmacology: The mediating role of expectations in the experience of side effects in anxious patients treated with secukinumab.

Brain, behavior, & immunity - health·2026

Related Experiment Videos

The pharmacokinetic basis of insulin therapy in diabetes mellitus

Related Concept Videos

Similar glycaemic control and risk of hypoglycaemia with patient- versus physician-managed titration of insulin glargine 300 U/mL across subgroups of patients with T2DM: a post hoc analysis of ITAS.

Italian Titration Approach Study (ITAS) with insulin glargine 300 U/mL in insulin-naïve type 2 diabetes: Design and population.

Clinical relevance of pharmacokinetic and pharmacodynamic profiles of insulin degludec (100, 200 U/mL) and insulin glargine (100, 300 U/mL) - a review of evidence and clinical interpretation.

Glycaemic control and hypoglycaemia risk with insulin glargine 300 U/mL versus glargine 100 U/mL: A patient-level meta-analysis examining older and younger adults with type 2 diabetes.

Assessment of hypoglycaemia during basal insulin therapy: Temporal distribution and risk of events using a predefined or an expanded definition of nocturnal events.

Morning administration of 0.4U/kg/day insulin glargine 300U/mL provides less fluctuating 24-hour pharmacodynamics and more even pharmacokinetic profiles compared with insulin degludec 100U/mL in type 1 diabetes.

Prediabetes phenotypes and the development and regression of metabolic dysfunction-associated fatty liver disease: A prospective cohort study.

Global insulin supply insecurity and the role of manufacturing innovation.

Association of peripheral neuropathy severity and cardiac autonomic dysfunction in individuals with neuropathic diabetic foot versus those with diabetic peripheral neuropathy alone.

Knowledge, health beliefs, and diabetic retinopathy screening practices among adults living with diabetes in Ebonyi state, Nigeria: a community-based cross-sectional study.

Impact of vaccination on the development of type 1 diabetes in children and vaccine safety in pediatric patients with T1DM: A systematic review.

Diabetes, Long-term mortality, and LDL-C target attainment after an acute coronary syndrome: A population-based cohort study (2016-2024).

Efficacy analysis and adverse event management of selinexor in the treatment of relapsed/refractory multiple myeloma.

Case Report: Panic attacks after tirzepatide injection in two female patients with recurrent depressive disorder.

Individualized dosing in the precision medicine era: a narrative review.

Targeting the Parkinson's disease interactome: a systems pharmacology and molecular dynamics investigation unveils Berberis aristata-derived phytoconstituents as potential modulators of tyrosine hydroxylase and p53: a systems and molecular dynamics investigation.

Transcriptomic insights into loperamide-induced gastric dysmotility: RNA-seq analysis of a mouse model.

Beyond pharmacology: The mediating role of expectations in the experience of side effects in anxious patients treated with secukinumab.

Related Experiment Videos

The pharmacokinetic basis of insulin therapy in diabetes mellitus

Related Concept Videos

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