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Published on: September 13, 2022
A signal-on split aptasensor for highly sensitive and specific detection of tumor cells based on FRET
Baoyin Yuan1, Yu Zhou, Qiuping Guo
1State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, College of Chemistry and Chemical Engineering, Hunan University, Key Laboratory for Bio-Nanotechnology and Molecule Engineering of Hunan Province, Changsha, 410082, China. kmwang@hnu.edu.cn guoqping@126.com.
Abstract:
We present here a signal-on fluorescence biosensor for highly sensitive and specific detection of tumor cells with a split aptamer based on fluorescence resonance energy transfer (FRET). This sensor holds considerable potential for simple, rapid, sensitive and specific tumor cell detection in early clinical diagnosis.
