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Updated: Mar 28, 2026

Merkel Cell Polyomavirus Infection and Detection
Published on: February 7, 2019
Trichodysplasia spinulosa: a polyomavirus infection specifically targeting follicular keratinocytes in
J Rouanet1,2, F Aubin3,4, P Gaboriaud5
1Department of Dermatology, Université d'Auvergne, CHU Clermont-Ferrand Hôpital Estaing, 63003, Clermont-Ferrand, France.
Abstract:
Trichodysplasia spinulosa (TS) is a rare skin disease, caused by a specific polyomavirus, occurring in immunocompromised patients. The pathophysiological mechanisms of TS are not yet fully understood. By using polymerase chain reaction and skin biopsy immunostaining we report evidence, in a paediatric case, of follicular keratinocytes being the primary target of trichodysplasia spinulosa-associated polyomavirus.
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