Clinical and pathological correlations in endometrial pathology.
R E Bohîlțea1, M Sajin1, F Furtunescu1
1"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Journal of Medicine and Life
|December 15, 2015
Summary
Endometrial cancer diagnosis in Romania relies heavily on dilation and uterine curettage, with abnormal uterine bleeding being the primary symptom. Early detection remains a challenge, impacting patient survival rates for this increasing cancer.
Area of Science:
- Gynecologic Oncology
- Pathology
- Public Health
Background:
- Endometrial cancer incidence and mortality rates are rising globally and in Romania.
- Accurate diagnosis is crucial for effective treatment and improved patient outcomes.
Purpose of the Study:
- To analyze the diagnostic approaches for endometrial pathology at a major Romanian hospital.
- To evaluate the effectiveness of current diagnostic methods for endometrial cancer.
Main Methods:
- Retrospective analysis of endometrial pathology cases over a four-year period.
- Dilation and uterine curettage (D&C) as the primary method for endometrial biopsy.
- Histopathological examination for diagnosis and staging.
Main Results:
- Dilation and uterine curettage confirmed diagnosis in 68.4% of endometrial pathology cases.
- Endometrial hyperplasia (54.9%) was more common than endometrial carcinoma (19%).
- 64.2% of endometrial cancer cases were diagnosed at stages limited to the uterus (IA, IB, IC), with endometrioid adenocarcinoma being the most frequent type.
Conclusions:
- Abnormal uterine bleeding is the key symptom leading to diagnosis in 66% of localized endometrial cancer cases.
- A significant portion (34%) of endometrial cancer cases are diagnosed at advanced stages, correlating with lower life expectancy.
- Improving early diagnostic strategies is essential to combat rising endometrial cancer mortality.
Keywords:
abnormal uterine bleedingclinical and pathological correlationsendometrial cancerendometrial carcinomaMore Related Videos
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