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Subcutaneous myospherulosis.

J S Waldman1, R J Barr, F P Espinoza

  • 1Department of Dermatology, University of California, Irvine.

Journal of the American Academy of Dermatology
|August 1, 1989
PubMed
Summary
This summary is machine-generated.

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Myospherulosis, a subcutaneous disorder, is not caused by fungus but by altered red blood cells, often from petrolatum or lanolin exposure. This case highlights a long-term reaction to a prior injection.

Area of Science:

  • Dermatology
  • Pathology

Background:

  • Myospherulosis was previously misattributed to fungal infection.
  • Recent research refutes an infectious etiology for this condition.

Observation:

  • A 57-year-old woman presented with a cystic mass in her right buttock.
  • The mass developed approximately 40 years after a penicillin injection.

Findings:

  • Histologic examination revealed the characteristic features of myospherulosis.
  • The disease is now understood as a response to altered red blood cells, typically induced by substances like petrolatum or lanolin, eliciting a foreign-body reaction.

Implications:

  • This case underscores the potential for delayed-onset foreign-body reactions to injected substances.

Related Experiment Videos

  • Understanding the non-infectious nature of myospherulosis is crucial for accurate diagnosis and management.