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Updated: Mar 28, 2026

A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse
Published on: December 16, 2022
Mirror Image Gerbode or Partial Atrioventricular Canal Defect?
Cem Ariturk1, Ahmet Umit Gullu1, Sahin Senay1
1Department of Cardiovascular Surgery, Acıbadem University.
A rare cardiac defect, a ventricular septal defect, was successfully repaired in a 74-year-old woman. This case highlights the importance of tailored surgical strategies for atrioventricular canal defects.
Area of Science:
- Cardiology
- Cardiac Surgery
Background:
- Ventricular septal defects (VSDs) represent abnormal communications between the left ventricle and right atrium, often requiring surgical intervention.
- Atrioventricular canal defects (AVCDs) necessitate careful preoperative assessment to determine the optimal surgical approach.
Observation:
- A 74-year-old female presented with worsening symptoms of orthopnea and peripheral edema, indicative of potential cardiac compromise.
- Transthoracic echocardiography revealed a significant communication between the right atrium and left ventricle, consistent with a VSD.
Findings:
- The diagnosed ventricular septal defect was surgically repaired.
- Concurrent mitral valve replacement with a biologic valve was performed during the same procedure.
Implications:
- This case underscores the efficacy of surgical repair for complex VSDs.
- Personalized surgical strategies, informed by preoperative echocardiography and intraoperative visualization, are crucial for successful AVCD management.
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