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Related Concept Videos

The Bone Matrix01:18

The Bone Matrix

8.6K
Bone contains a relatively small number of cells entrenched in a matrix of collagen fibers that provide an adherent surface for inorganic salt crystals. Both components of the matrix, organic and inorganic, contribute to the unusual properties of bone. Without collagen, bones would be brittle and shatter easily. Without mineral crystals, bones would flex and provide little support. This can be observed by an experiment: when the minerals of a bone are dissolved by soaking the bone in...
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Spongy Bone01:09

Spongy Bone

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All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
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Compact Bone01:27

Compact Bone

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Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
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Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

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The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
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Bone as Supporting Connective Tissue01:23

Bone as Supporting Connective Tissue

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Bone tissue forms the internal skeleton of vertebrate animals, providing structure to the body.
Bone Matrix
Bone, or osseous tissue, is a connective tissue that has a large amount of two different types of matrix material. The organic matrix is similar to the matrix material found in other connective tissues, including some amount of collagen and elastic fibers. This gives strength and flexibility to the tissue. The inorganic matrix consists of mineral salts— mostly calcium salts—...
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Bone Remodeling and Repair01:31

Bone Remodeling and Repair

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Updated: Mar 28, 2026

In situ Compressive Loading and Correlative Noninvasive Imaging of the Bone-periodontal Ligament-tooth Fibrous Joint
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Silicon and boron differ in their localization and loading in bone.

Ravin Jugdaohsingh1, Liliana D Pedro1, Abigail Watson2

  • 1MRC Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, United Kingdom.

Bone Reports
|December 15, 2015
PubMed
Summary
This summary is machine-generated.

Silicon and boron have different roles in bone development. Silicon binds to collagen, while boron associates with bone mineral, indicating they are not interchangeable in bone health.

Keywords:
B, boronBoneBone mineralisationBoronCollagenEDTA, ethylenediaminetetraacetic acidGrowth and developmentICP-OES, inductively coupled plasma-optical emission spectroscopySGIF, simulated gastrointestinal fluidSi, siliconSiliconUHP, ultra-high purity

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Area of Science:

  • Biochemistry
  • Bone Biology
  • Trace Element Metabolism

Background:

  • Silicon and boron share chemical similarities and influence bone health, but their specific mechanisms remain unclear.
  • Understanding the distinct roles of silicon and boron in bone is crucial for elucidating their biochemical functions.

Purpose of the Study:

  • To compare the uptake, localization, and age-related changes of silicon and boron in rat bone.
  • To determine if silicon and boron exhibit similar or different behaviors within bone tissue.

Main Methods:

  • Bone samples from female Sprague Dawley rats (up to 43 weeks) were analyzed.
  • Total bone elemental analysis using ICP-OES after microwave-assisted acid digestion.
  • Silicon and boron levels were quantified in both whole bone and decalcified (collagen) fractions.

Main Results:

  • Silicon and boron showed distinct loading patterns and localization in bone.
  • Younger rats had higher silicon and lower boron in less mineralized bone; adult rats showed the opposite.
  • Silicon distributed between collagen and mineral fractions, while boron was exclusively in the mineral fraction.

Conclusions:

  • Silicon is associated with collagen, particularly during early bone mineralization.
  • Boron is linked to bone mineral, not connective tissues, suggesting different biological roles.
  • Silicon and boron are unlikely to substitute for each other in bone metabolism; nutritional factors may influence silicon uptake.