[Clinico-pathologically focused breast cancer research]

Area of Science:

• Oncology
• Pathology
• Molecular Biology

Context:

• Breast cancer research at Semmelweis University historically centered at the 2nd Department of Pathology.
• Evolving breast cancer treatment necessitates novel predictive and prognostic markers.

Purpose:

• To review key breast cancer research findings from Semmelweis University between 2000 and 2015.
• To highlight the role of molecular pathology in understanding breast cancer biology.

Summary:

• The study reviews breast cancer research from 2000-2015, focusing on advancements in molecular pathology.
• Molecular pathological approaches are essential for characterizing individual breast cancers and guiding treatment.
• This approach supports more effective neoadjuvant, adjuvant, and metastatic breast cancer therapies.

Impact:

• Advances in molecular pathology improve the understanding of breast cancer's biological behavior.
• Identified markers enhance treatment strategies for various stages of breast cancer.
• Research contributes to more personalized and effective breast cancer management.