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[Research Advances in Postmortem Chemistry]
Fa Yi Xue Za Zhi
|December 16, 2015
Summary
Postmortem chemistry, analyzing bodily fluids, is crucial for determining cause of death when other methods fail. This review covers recent advances in biochemical analysis for forensic pathology.
Area of Science:
- Forensic Pathology
- Clinical Chemistry
- Toxicology
Background:
- Postmortem chemistry is increasingly vital in forensic pathology.
- Biochemical analysis of bodily fluids aids in determining cause of death and forensic investigations.
- It complements morphological methods for detecting subtle pathophysiological changes.
Purpose of the Study:
- To review recent advances in postmortem chemistry.
- To highlight the application of biochemical analyses in forensic pathology.
- To cover key areas including glucose metabolism, organ function, and specific conditions.
Main Methods:
- Review of recent scientific literature on postmortem chemistry.
- Focus on biochemical analyses of vitreous humor, blood, urine, and cerebrospinal fluid.
- Synthesis of findings related to glucose, liver, cardiac, and renal function, as well as sepsis, inflammation, infection, anaphylaxis, and hormonal aspects.
Main Results:
- Postmortem chemistry is essential when morphological findings are inconclusive.
- Biochemical markers provide insights into conditions like diabetes mellitus, alcoholic ketoacidosis, and electrolyte imbalances.
- Analysis can elucidate causes of death related to myocardial ischemia, sepsis, inflammation, infection, anaphylaxis, and hormonal disturbances.
Conclusions:
- Postmortem biochemical analysis is indispensable in modern forensic pathology.
- It offers critical data for determining cause of death and resolving forensic cases.
- Continued research in postmortem chemistry advances forensic investigations.

