[Research Advances in Postmortem Chemistry].

Area of Science:

• Forensic Pathology
• Clinical Chemistry
• Toxicology

Background:

• Postmortem chemistry is increasingly vital in forensic pathology.
• Biochemical analysis of bodily fluids aids in determining cause of death and forensic investigations.
• It complements morphological methods for detecting subtle pathophysiological changes.

Purpose of the Study:

• To review recent advances in postmortem chemistry.
• To highlight the application of biochemical analyses in forensic pathology.
• To cover key areas including glucose metabolism, organ function, and specific conditions.

Main Methods:

• Review of recent scientific literature on postmortem chemistry.
• Focus on biochemical analyses of vitreous humor, blood, urine, and cerebrospinal fluid.
• Synthesis of findings related to glucose, liver, cardiac, and renal function, as well as sepsis, inflammation, infection, anaphylaxis, and hormonal aspects.

Main Results:

• Postmortem chemistry is essential when morphological findings are inconclusive.
• Biochemical markers provide insights into conditions like diabetes mellitus, alcoholic ketoacidosis, and electrolyte imbalances.
• Analysis can elucidate causes of death related to myocardial ischemia, sepsis, inflammation, infection, anaphylaxis, and hormonal disturbances.

Conclusions:

• Postmortem biochemical analysis is indispensable in modern forensic pathology.
• It offers critical data for determining cause of death and resolving forensic cases.
• Continued research in postmortem chemistry advances forensic investigations.