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Therapeutic Application of Bone Marrow-Derived Stem Cells in a Patient with Methanol-Induced Blindness
Objective:
To report bone marrow derived stem cell application in a patient with bilateral visual loss due to accidental ingestion of methanol.
Method:
A 22-year-old male patient with bilateral visual loss at discharge after treatment for methanol ingestion was treated with retrobulbar and intrathecal autologus bone marrow derived stem cells in an outpatient setting. The procedure was followed by Vit B12 Injection 500 mcg alternate days and oral vitamins B1, B2, B6, in therapeutic dose for 3 months.
Result:
The patient demonstrated favorable outcome three days after the treatment. Visual acuity improved to 20/20 in both eyes by third week.
Conclusion:
Treatment with retrobulbar and intrathecal autologous bone marrow derived stem cell in an adult male patient with bilateral visual loss due to accidental ingestion of methanol was effective. Larger studies are warranted to explore the real impact of this procedure.
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