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A Nephrostomy-associated Urinary Tract Infection Caused by Elizabethkingia meningoseptica

Hideharu Hagiya1, Hiroko Ogawa, Yusuke Takahashi

  • 1Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan.

Internal Medicine (Tokyo, Japan)
|December 16, 2015
PubMed

Insights

A rare Elizabethkingia meningoseptica urinary tract infection (UTI) occurred in a patient with retroperitoneal fibrosis. Genetic sequencing confirmed the organism, and treatment with levofloxacin and minocycline was successful.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Genomics

Background:

  • Nephrostomy-associated urinary tract infections (UTIs) are a concern in patients with urinary tract abnormalities.
  • Retroperitoneal fibrosis can predispose patients to complex infections.
  • Elizabethkingia meningoseptica is an emerging pathogen, rarely implicated in UTIs.

Observation:

  • A patient with retroperitoneal fibrosis developed a nephrostomy-associated UTI.
  • Conventional microbiological methods failed to identify the causative agent.
  • Complete sequencing of the 16S rRNA gene was crucial for accurate organism identification.

Findings:

  • The causative organism was identified as Elizabethkingia meningoseptica.
  • The infection was successfully treated with a four-week course of levofloxacin and minocycline.
  • This represents the first genetically confirmed case of nephrostomy-associated UTI caused by E. meningoseptica.

Implications:

  • Accurate identification of E. meningoseptica is essential for effective treatment of UTIs.
  • This case highlights the importance of advanced molecular techniques in diagnosing challenging infections.
  • Further research into the epidemiology and pathogenicity of E. meningoseptica in urinary tract infections is warranted.

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