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Related Experiment Videos

[In Process Citation].

Gábor Horváth1, Zsuzsanna Gerlei2, Judit Gervain3

  • 1Hepatológiai Szakambulancia, Budai Hepatológiai Centrum, Budapest, Szent János Kórház és Észak-budai Egyesített Kórházak Budapest, Egry József u. 1-3. 1111.

Orvosi Hetilap
|December 16, 2015
PubMed
Summary
This summary is machine-generated.

This guideline provides 2016 treatment algorithms for Hepatitis B (HBV) and Hepatitis D (HDV) infections. It emphasizes timely virologic evaluation and appropriate follow-up for effective patient management and reduced transmission.

Keywords:
adefovircirrhosisentecavirhepatitis B virushepatitis B-vírushepatitis D virushepatitis D-vírusinterferonlamivudinlamivudineliver cancermájrákmájzsugorpegilált interferonpegylated interferontenofovirviral hepatitisvírushepatitis

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Area of Science:

  • Hepatology
  • Virology
  • Infectious Diseases

Context:

  • HBV/HDV infection impacts patient quality of life and societal health by posing cancer risks and transmission potential.
  • Prevalence of HBV in Hungary is 0.5-0.7%, necessitating clear treatment guidelines.
  • Physician consensus meetings established the 2016 treatment algorithms.

Purpose:

  • To delineate treatment algorithms for HBV/HDV infection.
  • To guide physicians on patient management for improved outcomes and reduced transmission.
  • To outline indications for treatment based on viral load, disease activity, and contraindications.

Summary:

  • Treatment indications require viral examinations, disease activity/stage assessment, and exclusion of contraindications.
  • Recommends pegylated interferon, entecavir, or tenofovir as first-line therapies for chronic Hepatitis B.
  • Pegylated interferon is recommended for concomitant Hepatitis D infection.

Impact:

  • Ensures patients maintain working capacity, enhance quality of life, prevent cancer, and prolong life expectancy.
  • Reduces viral transmission, benefiting society by decreasing the burden of serious complications.
  • Promotes cost-effective treatment through detailed virologic evaluations and elastography as a biopsy alternative.