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Updated: Mar 28, 2026

Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry
Published on: October 18, 2019
Enantioselective Hydrosilylation of Imines Catalyzed by Chiral Zinc Acetate Complexes
Agata Bezłada1, Marcin Szewczyk1, Jacek Mlynarski1
1Faculty of Chemistry, Jagiellonian University , Ingardena 3, 30-060 Krakow, Poland.
Abstract:
A series of zinc acetate complexes with optically pure diphenylethanediamine (DPEDA)-derived ligands have been employed as enantioselective catalyst for the hydrosilylation of various imines. High control of stereoselectivity (up to 97% ee) and excellent yields (up to 96%) were gained for a broad range of N-phosphinoylimines by using (R,R)-N,N'-dibenzyl-1,2-diphenylethane-1,2-diamine. This is the first successful application of an air-stable and environmentally friendly chiral Zn(OAc)2 complex instead of the previously used harmful diethylzinc in the asymmetric reduction of the C═N double bond.
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