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Updated: Mar 28, 2026

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
Published on: January 20, 2010
Tracheobronchopathia osteochondroplastica
Caleb Simmons1, Daniel Vinh2, Donald T Donovan1
1Department of Otolaryngology-Head & Neck Surgery, Baylor College of Medicine, Houston, Texas, U.S.A.
Abstract:
Tracheobronchopathia osteochondroplastica (TBOC) is a rare disease of the trachea and bronchi characterized by submucosal nodules of osseous and cartilaginous tissue. In this series, we present three cases highlighting the varied clinical presentations of this rare disease process, which ranged from a rough voice to a chronic cough to lobar pneumonia. The disorder may mimic other lesions. We review the clinical presentations, pathophysiology, lab tests, imaging, diagnosis, and management of TBOC patients. Laryngoscope, 126:2006-2009, 2016.
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