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Updated: Mar 28, 2026

Tissue Engineering of the Intestine in a Murine Model
Published on: December 1, 2012
[INTESTINAL FAILURE IN PEDIATRIC PATIENTS: EXPERIENCE AND MANAGEMENT BY A MULTIDISCIPLINARY GROUP]
Adriana Giraldo Villa1, María Isabel Martínez Volkmar1, Andrés Felipe Valencia Quintero1
1Grupo de Soporte Nutricional Pediátrico del Hospital Pablo Tobón Uribe. Colombia.. agiraldov.giraldo@gmail.com.
Insights
Multidisciplinary care improves outcomes for pediatric patients with intestinal failure. This approach led to high rates of intestinal autonomy and improved nutritional status in a retrospective study.
Area of Science:
- Pediatric Gastroenterology
- Clinical Nutrition
- Health Services Research
Background:
- Multidisciplinary teams enhance patient outcomes in intestinal failure.
- Integrated management and communication are crucial for pediatric intestinal failure care.
Purpose of the Study:
- To describe the multidisciplinary management strategies.
- To evaluate outcomes in pediatric patients with intestinal failure.
Main Methods:
- Retrospective study of pediatric patients (≤18 years) requiring Total Parenteral Nutrition (TPN).
- Analysis of qualitative and quantitative variables including nutritional support, concomitant treatments, and social work evaluations.
- Statistical analysis using frequencies, percentages, and measures of central tendency and dispersion.
Main Results:
- 33 patients with median follow-up of 281 days were analyzed.
- Intestinal autonomy achieved in 69.7% of cases, with significant weight gain (72.7%) and improved albumin levels.
- Common treatments included oral/enteral nutrition, ursodeoxycholic acid, cholestyramine, loperamide, antibiotics, and probiotics.
Conclusions:
- Managing pediatric intestinal failure presents challenges requiring standardized protocols.
- A multidisciplinary group approach is essential for effective patient care and improved outcomes.
Background:
institutions with multidisciplinary teams have shown improvements in patient outcomes with intestinal failure. Multidisciplinary approach allows an integral management and effective communication between families and care teams.
Objective:
describe the multidisciplinary management and outcome in pediatric patients with intestinal failure.
Methods:
retrospective study in patients 18 years old or less, with intestinal failure and Total Parenteral Nutrition (TPN) required. Simple frequencies and percentages were used for qualitative variables, and central tendency and dispersion measures were used for quantitative variables.
Results:
33 patients with a median follow up of 281 days were evaluated. The median duration of the TPN was 68 days and the mean of catheter-related infections was 2.26 per patient. In 31 patients oral or enteral nutrition was provided, starting in 61.3% of cases through tube and continuous infusion. As concomitant treatment 72.7% of children received ursodeoxycholic acid, 67.7%, cholestyramine 57.6% loperamide, 48.5% antibiotics and 36.4% probiotic. The families of 24 patients were evaluated by social work professionals. Intestinal autonomy was achieved in 69.7% of cases, 72.7% of them showed an improvement in the score z of weight and showed an end albumin significantly higher than the initial (p value: 0.012).
Conclusions:
the management of patients with intestinal failure is a challenge for health institutions and require care based on a standardized protocol and a multidisciplinary group.
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