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Asthma Detection Research Based on Voice Signal Processing and Machine Learning
Published on: July 22, 2025
Predicting future emergency department visits and hospitalizations for asthma using the Pediatric Asthma Control and
Dominic J Wu1, Evelyn Hipolito2, Andrew Bilderback3
1a W. Alpert Medical School of Brown University , Providence , RI , USA .
Insights
The Pediatric Asthma Control and Communication Instrument - Emergency Department version (PACCI-ED) can predict future asthma-related emergency department visits. Questions on prior emergency department visits and hospitalizations within the PACCI-ED are most effective for risk screening.
Area of Science:
- Pediatric emergency medicine
- Respiratory health outcomes
- Clinical informatics
Background:
- Emergency departments (EDs) are crucial for managing pediatric asthma exacerbations.
- Effective screening tools are needed in EDs to identify children at high risk for future asthma-related morbidity.
- The Pediatric Asthma Control and Communication Instrument - Emergency Department version (PACCI-ED) was developed for this purpose.
Purpose of the Study:
- To evaluate the predictive validity of the PACCI-ED for future asthma-related emergency department (ED) visits and hospitalizations in children.
- To determine which components of the PACCI-ED are most effective in predicting these outcomes.
Main Methods:
- A retrospective cohort study involving 108 children (1-17 years) treated for asthma in an ED.
- Children completed the PACCI-ED, which assesses prior asthma history, perceived burden, and control.
- Subsequent ED visits and hospitalizations within one year were tracked as primary outcomes.
- Poisson regression analysis was used to model the predictive value of PACCI-ED questions, controlling for age and socioeconomic status.
Main Results:
- Parent-reported prior ED visits predicted future ED visits (aIRR 3.1).
- Parent-reported prior hospitalizations predicted future ED visits (aIRR 3.3) and future hospitalizations (aIRR 6.4).
- No other PACCI-ED questions or domains demonstrated predictive validity for future asthma-related healthcare utilization.
Conclusions:
- The risk domain of the PACCI-ED, specifically questions about previous ED visits and hospitalizations, effectively predicts future asthma-related ED visits and hospitalizations.
- These specific questions are valuable for screening children with asthma in the ED setting to identify those at higher risk for future healthcare needs.
Objective:
Emergency departments (EDs) are potential settings for interventions to improve asthma outcomes. Screening tools can identify children at risk of future morbidity. Our objective was to determine the predictive validity of the Pediatric Asthma Control and Communication Instrument - Emergency Department version (PACCI-ED) for future asthma-related ED visits and hospitalizations.
Methods:
This was a retrospective cohort study of 108 children 1-17 years old who visited an ED for asthma and completed the PACCI-ED. The PACCI-ED queries parents about prior 12-month ED visits, hospitalizations, steroid use, perceived asthma morbidity and burden, and asthma control (over prior 1-2 weeks). The primary outcome was subsequent ED visits and hospitalizations within 1 year of enrollment. Poisson regression was used to model PACCI-ED questions for future ED visits controlling for age and socioeconomic status.
Results:
Reported ED visits predicted future ED visits (adjusted incidence rate ratio (aIRR) 3.1, 95% confidence interval (CI): 1.3-7.2) but not future hospitalizations. Reported hospitalizations predicted future ED visits (aIRR 3.3; 95% CI 1.7-6.3) and hospitalizations (aIRR 6.4; 95% CI 2.3-17.6). The remaining PACCI-ED questions did not predict future ED visits or hospitalizations.
Conclusions:
The PACCI-ED risk domain was the only domain that predicted future asthma ED visits and hospitalizations. Questions about previous ED visits and hospitalizations are the most effective questions when screening children with asthma in EDs for the risk of future health-care use.
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