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Updated: Mar 28, 2026

Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation
Published on: June 3, 2018
Three-Dimensional Rotational Angiography in the Pediatric Cath Lab: Optimizing Aortic Interventions
Anna Stenger1, Sven Dittrich2, Martin Glöckler2
1Department of Pediatric Cardiology, University Hospital Erlangen, "Friedrich-Alexander-University Erlangen-Nürnberg (FAU)", Loschgestrasse 15, 91054, Erlangen, Germany. anna.stenger@uk-erlangen.de.
Insights
Three-dimensional rotational angiography (3DRA) is accurate and fast for aortic interventions in congenital heart disease (CHD). This imaging technique improves diagnostic accuracy, simplifies procedures, and potentially reduces radiation exposure for patients.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Congenital heart disease (CHD) often involves aortic anomalies requiring interventions.
- Limited data exists on the use of three-dimensional rotational angiography (3DRA) in CHD aortic interventions.
Purpose of the Study:
- To evaluate the usability and accuracy of 3DRA during aortic interventions in patients with CHD.
- To compare 3DRA with conventional angiography in terms of accuracy, procedure time, and radiation dose.
Main Methods:
- Retrospective analysis of 77 patients with aortic issues undergoing 3DRA between January 2010 and January 2014.
- Accuracy assessed by comparing aortic diameter measurements between 3DRA and conventional biplane angiography (n=60).
- Clinical benefit evaluated using a Likert scale; fluoroscopy time and radiation dose compared to a control group.
Main Results:
- 3DRA showed high accuracy in aortic diameter measurements (average deviation 3.89%, r=0.99, p<0.0001).
- Clinical benefit was observed in 98% of cases.
- Reduced median fluoroscopy time (10.2 to 8.30 min, p<0.01) and radiation dose (0.18 vs 0.56 Gy cm(2)/kg, p<0.02) were noted.
Conclusions:
- 3DRA is an accurate and effective imaging technique for aortic interventions in CHD patients.
- It offers improved diagnostic accuracy and procedural simplification compared to conventional angiography.
- 3DRA enhances patient safety and has the potential to reduce radiation exposure.
Abstract:
The aim of this study was to evaluate usability and accuracy of three-dimensional rotational angiography (3DRA) during interventions of the aorta in congenital heart disease (CHD). 3DRA is an accurate, encompassing and fast imaging technique in the cath lab. However, there is only few published data about its use during interventions in CHD. Between January 2010 and January 2014, 3DRA was performed in 77 patients with aortic issues: in 65 % cases, an intervention was performed, of which 72 % had aortic isthmus stenosis. Data were obtained retrospectively. The accuracy of 3DRA was evaluated on the basis of comparative measurements (n = 60) of the aortic diameter between 3DRA and conventional biplane angiography. Measurements presented a high accuracy with an average deviation of 3.89 % [±3 %] and a significant correlation of r = 0.99 after Pearson (p < 0.0001). Clinical benefit was assessed using a five-point Likert scale and could be shown in 98 %. Comparison with a control group showed a reduced fluoroscopy time from 10.2 to 8.30 min (median, p < 0.01) and decreased radiation dose of 0.18 compared to 0.56 Gy cm(2)/kg (median, p < 0.02). The use of 3DRA in patients with aortic anomalies has advantages in comparison with conventional angiography. It improves diagnostic accuracy, and 3D guidance enables a faster and simplified intervention with enhanced patients' safety and the potential to reduce radiation dose.
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