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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Updated: Mar 28, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
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A 3D Organotypic Melanoma Spheroid Skin Model

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Malignant melanoma maxilla.

Seema Devi1, Richi Sinha1, Rakesh Kumar Singh1

  • 1Department of Radiation Oncology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar India.

National Journal of Maxillofacial Surgery
|December 16, 2015
PubMed
Summary

Malignant melanoma, a rare skin cancer, can aggressively affect the head and neck. This case report details a 35-year-old male with advanced nasal malignant melanoma and subsequent liver metastasis.

Area of Science:

  • Oncology
  • Dermatology
  • Pathology

Background:

  • Malignant melanoma is a lethal neoplasm originating from melanocytes.
  • Head and neck melanomas represent less than 1% of all melanoma cases.
  • Nasal and paranasal sinus melanomas are aggressive and often diagnosed at advanced stages.

Observation:

  • This case report focuses on a 35-year-old male patient.
  • The patient presented with a highly aggressive form of the disease.
  • The neoplasm affected the nasal and paranasal sinus region.

Findings:

  • The patient developed liver metastasis, indicating systemic spread.
  • The 5-year survival rate for this condition is low, ranging from 20-30%.

Implications:

Keywords:
Melanocytesmelanomaneuroectoderm

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  • Highlights the aggressive nature of sinonasal malignant melanoma.
  • Underscores the importance of early diagnosis and treatment strategies.
  • Emphasizes the potential for rapid metastasis in advanced cases.