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Assessment of Systemic Inflammatory Markers in Patients with Aggressive Periodontitis
P Safar Iqbal1, S Nubesh Khan2, Mohamed Haris3
1Assistant Professor, Department of Periodontics, Malabar Dental College, Kerala, India.
Journal of International Oral Health : JIOH
|December 16, 2015
Summary
Aggressive periodontitis (AgP) is linked to increased systemic inflammation markers and decreased serum proteins. These changes suggest AgP may be a risk factor for cardiovascular diseases.
Area of Science:
- Periodontology
- Immunology
- Systemic Health
Background:
- Aggressive periodontitis (AgP) is a severe gum disease causing rapid tissue loss.
- Systemic inflammation may link AgP to other health issues.
- Understanding AgP's systemic impact is crucial.
Purpose of the Study:
- To evaluate systemic inflammatory markers in patients with AgP.
- To compare these markers between AgP patients and healthy individuals.
Main Methods:
- 50 systemically healthy participants were divided into two groups: 25 healthy and 25 with AgP.
- Blood tests measured white blood cell (WBC), neutrophil, lymphocyte, and platelet counts.
- Serum protein levels (total protein, albumin, globulin) were analyzed.
Main Results:
- AgP patients showed higher WBC, neutrophil, lymphocyte, and platelet counts.
- AgP patients exhibited lower total protein, albumin, and globulin levels.
- Significant differences in inflammatory and protein markers were observed between groups.
Conclusions:
- AgP is associated with elevated systemic inflammatory markers and reduced serum proteins.
- These alterations suggest AgP may be a risk factor for cardiovascular diseases.
- Further research is warranted to confirm the link between AgP and cardiovascular outcomes.
