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Related Concept Videos

Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

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Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
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Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
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Interval colorectal carcinoma: An unsolved debate.

Mark Benedict1, Antonio Galvao Neto1, Xuchen Zhang1

  • 1Mark Benedict, Xuchen Zhang, Department of Pathology, Yale University School of Medicine, New Haven, CT 06520, United States.

World Journal of Gastroenterology
|December 16, 2015
PubMed
Summary

Interval colorectal cancers (CRCs) are a significant concern, developing after negative screenings. Research indicates multiple factors contribute to their occurrence, but rates are declining due to improved understanding and technology.

Keywords:
Colorectal carcinomaDetectionInterval colorectal carcinomaPost colonoscopy colorectal cancerScreening

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Area of Science:

  • Gastroenterology
  • Oncology
  • Cancer Research

Background:

  • Colorectal carcinoma (CRC) is a leading cause of cancer diagnosis.
  • Interval CRCs, diagnosed after negative screening, represent a critical challenge.
  • Factors influencing interval CRC development include procedural quality, endoscopist experience, and patient genetics.

Discussion:

  • The multifactorial nature of interval CRCs necessitates a comprehensive approach to prevention.
  • Missed or incompletely excised lesions are significant contributors to interval CRC.
  • Advances in screening technology and a deeper understanding of interval disease have led to a decrease in interval CRC rates.

Key Insights:

  • Interval CRC development is influenced by a complex interplay of factors.
  • Technological advancements and improved screening protocols are crucial in reducing interval CRC incidence.
  • Continued research into the causes and prevention of interval CRCs is essential.

Outlook:

  • Future research should focus on refining screening techniques and improving detection methods for early-stage colorectal cancers.
  • Personalized screening strategies based on individual risk factors may further reduce interval CRC rates.
  • Enhanced endoscopist training and quality metrics are vital for minimizing missed lesions.