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Related Concept Videos

Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
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Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
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Related Experiment Video

Updated: Mar 28, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
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[SCLEROSIS: LOCAL AND GENERAL PATTERNS OF DEVELOPMENT].

Ya A Kats, E V Parkhonyuk

    Klinicheskaia Meditsina
    |December 17, 2015
    PubMed
    Summary
    This summary is machine-generated.

    Sclerosis, a common outcome of various diseases, impacts disease severity. Understanding its development requires integrated analysis for personalized, predictive medicine strategies.

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    Area of Science:

    • Pathology and Medicine
    • Fibrosis Research
    • Systemic Diseases

    Context:

    • Sclerosis represents a common endpoint in diverse pathological conditions affecting multiple organs.
    • It frequently dictates the severity and prognosis of diseases like hypertension, heart disease, and autoimmune disorders.
    • Understanding sclerosis is crucial for managing a wide range of chronic illnesses.

    Purpose:

    • To elucidate the general patterns of sclerosis development.
    • To highlight the necessity of an integrated approach combining systemic and local analyses.
    • To explore the application of predictive-preventive personalized medicine in sclerosis treatment.

    Summary:

    • Sclerosis, a structural tissue lesion, is a common outcome in conditions such as hypertensive disease, coronary heart disease, chronic obstructive pulmonary disease, systemic lupus erythematosus, rheumatoid arthritis, and systemic scleroderma.
    • It often determines disease severity and prognosis.
    • Integrated analysis of clinical, genetic, biochemical, and morphological data, alongside local patient-specific factors, is essential for understanding sclerosis development.

    Impact:

    • Facilitates a comprehensive understanding of sclerosis across various diseases.
    • Enables the development of targeted therapies based on integrated patient data.
    • Paves the way for personalized medicine approaches in predicting and preventing sclerosis progression.