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Updated: Mar 28, 2026

Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice
Published on: February 2, 2019
Reliability of Time to Exhaustion Treadmill Running as a Measure of Human Endurance Capacity
A F Alghannam1, D Jedrzejewski1, M Tweddle1
1Department for Health, University of Bath, Bath, United Kingdom.
Abstract:
Little if any research has examined the variability in time to exhaustion (TTE) during submaximal treadmill running. This study investigated the test-retest reliability of submaximal treadmill TTE as a measure of endurance capacity. 16 endurance-trained males (n=14) and females (n=2) completed a run to exhaustion at 70% V̇O2max (T1) and repeated the same run 3 weeks later (T2). At 30-min intervals during each run, expired gas, heart rate (HR) and ratings of perceived exertion (RPE) were collected. Mean ± SD TTE was 96 ± 20 min in T1 vs. 101 ± 29 min in T2 (P=0.3). The mean ± 95% confidence intervals (CI) of the coefficient of variance (CV) was 5.4% (1.4-9.6). The average intraclass correlation coefficient (± 95% CI) was 0.88 (0.67-0.96) between trials. The respiratory-exchange ratio was not different between trials, T1: 0.87 ± 0.1 and T2: 0.89 ± 0.1 (P>0.05) and neither was total whole-body carbohydrate oxidation (2.1 ± 0.4 g·min(-1) and 2.3 ± 0.6 g·min(-1)), fat oxidation (0.6 ± 0.2 g·min(-1)), HR (178 ± 8 and 175 ± 7 beats·min(-1)) or RPE (17 ± 3 and 16 ± 3). These results suggest that use of prolonged treadmill-based TTE can be a reliable research tool to assess human endurance capacity in aerobically-trained men and women.

