Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pancreatic function testing. Methods to identify exocrine insufficiency.

N H Gilinsky1

  • 1Department of Medicine, University of Kentucky College of Medicine, Lexington.

Postgraduate Medicine
|August 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Use of omeprazole in the management of giant duodenal ulcer: results of a prospective study.

Surgery·1999
Same author

Arterial oxygen saturation during emergency esophagogastroduodenoscopy. The effects of nasal oxygen.

Journal of clinical gastroenterology·1994
Same author

Colonic tumors.

Endoscopy·1994
Same author

Pancreatitis in patients with end-stage renal disease.

Medicine·1994
Same author

Limitations of percutaneous endoscopic jejunostomy.

JPEN. Journal of parenteral and enteral nutrition·1993
Same author

A multicenter, double-blind, randomized, placebo-controlled comparison of nocturnal roxatidine in the treatment of active duodenal ulcer disease. Multicenter Roxatidine Cooperative Study Group.

The American journal of gastroenterology·1992
Same journal

Clinical pharmacokinetics of colistimethate sodium and formed colistin in patients with renal impairment or on dialysis modalities: a systematic review and implications for precision dosing.

Postgraduate medicine·2026
Same journal

The role of type D personality in pregnancy symptom severity, functional limitations, and maternal ambivalence.

Postgraduate medicine·2026
Same journal

Operational and demographic predictors of leaving without being seen in a high-volume tertiary emergency department: a five-year case-control study.

Postgraduate medicine·2026
Same journal

Risk of adverse effects of the concomitant use of statins with calcium channel blockers: a systematic review and meta-analysis.

Postgraduate medicine·2026
Same journal

Association between frailty and major chronic disease-free life expectancy: a large community-based longitudinal study.

Postgraduate medicine·2026
Same journal

The prevalence of functional iron deficiency and its impact on mortality in patients receiving hemodialysis.

Postgraduate medicine·2026
See all related articles

Diagnosing chronic pancreatitis often requires pancreatic function tests when imaging is unclear. Modified indirect tests offer improved accuracy for detecting early exocrine dysfunction and monitoring treatment.

Area of Science:

  • Gastroenterology
  • Digestive Health
  • Pancreatic Diseases

Background:

  • Chronic pancreatitis diagnosis relies on clinical history and imaging.
  • Normal or equivocal imaging necessitates pancreatic function testing.
  • Direct intubation tests are gold standard but invasive; indirect tests are simpler.

Purpose of the Study:

  • To evaluate the utility of pancreatic function tests in diagnosing chronic pancreatitis.
  • To assess the sensitivity and specificity of indirect pancreatic function tests.
  • To explore the role of modified indirect tests in detecting early exocrine dysfunction.

Main Methods:

  • Review of direct (intubation) and indirect pancreatic function tests.
  • Analysis of modified indirect tests like the two-stage paraaminobenzoic acid test and pancreolauryl test.

Related Experiment Videos

  • Comparison of test performance in differentiating pancreatic exocrine dysfunction from other causes of steatorrhea.

    • Main Results:

    • Direct tests are accurate but invasive.
    • Standard indirect tests lack sensitivity for early exocrine dysfunction.
    • Modified indirect tests show improved specificity and can distinguish pancreatic causes of steatorrhea.
    • Reproducibility of modified tests is valuable for monitoring disease progression and treatment compliance.

    Conclusions:

    • Modified indirect pancreatic function tests are valuable tools when imaging is inconclusive.
    • These tests aid in diagnosing early exocrine dysfunction and monitoring treatment effectiveness.
    • Indirect tests offer a less invasive, more accessible option for assessing pancreatic exocrine capacity.