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[Overactive bladder syndrome--a public health challenge].
Revue Medicale Suisse
|December 18, 2015
Summary
Overactive bladder (OAB) affects many women, causing distress and often going untreated. Treatment options range from physiotherapy and medications to nerve stimulation and botulinum toxin injections.
Area of Science:
- Urology
- Gynecology
- Pharmacology
Context:
- Overactive bladder (OAB) is a common condition affecting up to 17% of women.
- It is frequently under-diagnosed and inadequately treated, impacting quality of life.
- The pathophysiology of OAB is complex, necessitating diverse therapeutic approaches.
Purpose:
- To provide an overview of current treatment modalities for overactive bladder.
- To highlight the role of various interventions when initial therapies are ineffective.
- To discuss emerging treatments for idiopathic overactive bladder.
Summary:
- First-line medical treatment for OAB typically involves anticholinergics when physiotherapy is insufficient.
- Beta3-adrenergic agonists can be used as alternatives or in combination with anticholinergics.
- Sacral neuromodulation, posterior tibial nerve stimulation, and botulinum toxin injections are effective alternative or advanced treatments.
Impact:
- Improved quality of life for patients suffering from overactive bladder symptoms.
- Enhanced understanding of the treatment landscape for a prevalent clinical syndrome.
- Validation of novel therapeutic options like botulinum toxin for idiopathic OAB.
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