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[Progress in industrial bioprocess engineering in China].

Yingping Zhuang, Hongzhang Chen, Jianye Xia

Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology

|December 18, 2015

Summary

Industrial biotechnology advances rely on bioprocess research. China

Area of Science:

Industrial biotechnology
Bioprocess engineering
Fermentation technology

Background:

Industrial biotechnology's progress is tied to bioprocess research.
China's large industrial fermentation capacity presents unique challenges.
Bioprocess development in China has evolved through distinct stages.

Observation:

Early research focused on kinetics models from chemical engineering.
Control theory-based methods were applied to bioprocess research.
Advancements include multi-parameter on-line analysis and multi-scale theories.

Findings:

Review covers 30-40 years of Chinese industrial bioprocess development.
Key areas include kinetics, control theory, and advanced analytical techniques.

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Solid-state fermentation techniques and fermenter development are also discussed.

Implications:

Understanding China's bioprocess evolution informs future research directions.
Highlights the integration of chemical engineering principles and advanced technologies.
Provides insights into overcoming challenges in large-scale industrial fermentation.