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Updated: Mar 28, 2026

Utilizing the Antigen Capsid-Incorporation Strategy for the Development of Adenovirus Serotype 5-Vectored Vaccine Approaches
Published on: May 6, 2015
[Is there a risk of zoonotic disease due to adenoviruses?]
Fabien Loustalot1, Sophie Creyssels1, Sara Salinas1
1Institut de Génétique Moléculaire de Montpellier, CNRS UMR 5535, 1919, route de Mende, 34293 Montpellier, France - Université de Montpellier, Montpellier, France.
Abstract:
Every year brings another round of zoonotic viral infections. Usually they fall under the radar, but the occasional lethal epidemic brings another scare to the public and new urgency to the medical community. The types of these viruses (DNA vs. RNA genomes, enveloped vs. proteinaceous) as well as the preceding host(s) vary. Over the last 20 years, bats have been identified as an enigmatic carrier for several pathogens that have jumped the species barrier and infected humans. Factors that favour the emergence of zoonotic pathogens include the increasing overlap of the human and animal habitats, cultural activities, and the host reservoir. In this context, we asked whether bat and/or nonhuman primate adenoviruses are a risk for human health.
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