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Updated: Mar 28, 2026

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
Published on: February 16, 2022
Application of nitric oxide measurements in clinical conditions beyond asthma
Andrei Malinovschi1, Dora Ludviksdottir2, Ellen Tufvesson3
1Department of Medical Sciences: Clinical Physiology, Uppsala University, Uppsala, Sweden; Andrei.Malinovschi@medsci.uu.se.
Abstract:
Fractional exhaled nitric oxide (FeNO) is a convenient, non-invasive method for the assessment of active, mainly Th2-driven, airway inflammation, which is sensitive to treatment with standard anti-inflammatory therapy. Consequently, FeNO serves as a valued tool to aid diagnosis and monitoring in several asthma phenotypes. More recently, FeNO has been evaluated in several other respiratory, infectious, and/or immunological conditions. In this short review, we provide an overview of several clinical studies and discuss the status of potential applications of NO measurements in clinical conditions beyond asthma.
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